Experts from the Democratic Republic of Congo (DRC), Ethiopia, Kenya, South Sudan and Uganda convened in Entebbe, Uganda, to identify and discuss opportunities to strengthen cross-border interventions for guinea worm disease eradication. Participants mapped a joint action plan for 2018 to strengthen surveillance, communication and coordination for guinea worm disease eradication. They further charted a strategy to strengthen cross-border surveillance among refugees to prevent the disease from spilling over to refugee host-communities.