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Since January 1, 2022, Mpox cases have been reported to WHO from 21 Member States within the WHO African Region. As of December 1, 2024, a total of 17,188 laboratory-confirmed cases, including 79 deaths, have been reported. 

In 2024 alone, as of December 1, 19 countries have reported 14,849 confirmed cases, including 58 deaths. The majority of cases in 2024 have been reported from three countries: the Democratic Republic of the Congo (11,155 cases), Burundi (2,334 cases), and Uganda (817 cases). 

In the last 6 week from 1 December 2024, 13 countries have collectively reported 2 746 laboratory confirmed cases with three deaths (CFR=0.1) trends in the last 6 weeks compared to the 2 609 cases and 15 deaths (CFR=0.6) in the previous 6 weeks). 

Note: A significant number of suspected cases, that are clinically compatible with mpox are not tested due to limited diagnostic capacity and never get confirmed. For this reason, suspected cases (where no tests were done or with pending laboratory results) are also shown in this section. Care should be taken when interpreting these cases, as they are collected according to different case definitions. In some countries, suspected cases that are negative after laboratory tests are not removed from case counts. Not all countries have robust surveillance systems for mpox, so case counts are likely to be underestimated.